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1

New developments for prevention of type 1 diabetes: a paradigm shift?

Schofield, Christopher J, Sutherland, Calum

Journal:

British Journal of Hospital Medicine

Year:

2019

Language:

english

File:

PDF, 81 KB

english, 2019

2

Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element

David Finlay, Satish Patel, Lorna M Dickson, Natalia Shpiro, Rodolfo Marquez, Chris J Rhodes, Calum Sutherland

Journal:

BMC Molecular Biology

Year:

2004

Language:

english

File:

PDF, 2.30 MB

english, 2004

3

The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K+channels in the rat insulinoma cell line, CRI-G1

Jackie M Kinsella, Hilary A Laidlaw, Teresa Tang, Jenni Harvey, Calum Sutherland, Michael LJ Ashford

Journal:

BMC Pharmacology

Year:

2004

Language:

english

File:

PDF, 1.47 MB

english, 2004

4

Molecular connexions between dementia and diabetes

Adam R. Cole, Arlene Astell, Charlotte Green, Calum Sutherland

Journal:

Neuroscience & Biobehavioral Reviews

Year:

2007

Language:

english

File:

PDF, 484 KB

english, 2007

5

Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

Marc P. M. Soutar, Woo-Yang Kim, Ritchie Williamson, Mark Peggie, Charles James Hastie, Hilary McLauchlan, William D. Snider, Phillip R. Gordon-Weeks, Calum Sutherland

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 611 KB

english, 2010

6

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

Clayton, Emma L, Sue, Nancy, Smillie, Karen J, O'Leary, Timothy, Bache, Nicolai, Cheung, Giselle, Cole, Adam R, Wyllie, David J, Sutherland, Calum, Robinson, Phillip J

Journal:

Nature Neuroscience

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

7

Implications of genome wide association studies for the understanding of type 2 diabetes pathophysiology

John R. Petrie, Ewan R. Pearson, Calum Sutherland

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 257 KB

english, 2011

8

Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATPchannel activation

Shirin Mirshamsi, Hilary A Laidlaw, Ke Ning, Erin Anderson, Laura A Burgess, Alexander Gray, Calum Sutherland, Michael LJ Ashford

Journal:

BMC Neuroscience

Year:

2004

Language:

english

File:

PDF, 4.35 MB

english, 2004

9

Anaesthesia generates neuronal insulin resistance by inducing hypothermia

Christian Holscher, Lidy van Aalten, Calum Sutherland

Journal:

BMC Neuroscience

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

10

Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2 : Identification of two threonines phosphorylated during activation by mitogen-activated protein kinase

Calum SUTHERLAND, David G. CAMPBELL, Philip COHEN

Journal:

Year:

1993

Language:

english

File:

PDF, 902 KB

english, 1993

11

Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2

Calum SUTHERLAND, Janine ALTERIO, David G. CAMPBELL, Béatrice LE BOURDELLÈS, Jacques MALLET, Jan HAAVIK, Philip COHEN

Journal:

Year:

1993

Language:

english

File:

PDF, 945 KB

english, 1993

12

Esterification and absorption of cholesterol: in vitro and in vivo observations in the rat

Robert J. Williams, Alun D. McCarthy, Calum D. Sutherland

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1989

Language:

english

File:

PDF, 714 KB

english, 1989

13

The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

Calum Sutherland, Philip Cohen

Journal:

Year:

1994

Language:

english

File:

PDF, 643 KB

english, 1994

14

High fat feeding promotes simultaneous decline in insulin sensitivity and cognitive performance in a delayed matching and non-matching to position task

Alison D. McNeilly, Ritchie Williamson, Calum Sutherland, David J.K. Balfour, Caroline A. Stewart

Journal:

Behavioural Brain Research

Year:

2011

Language:

english

File:

PDF, 259 KB

english, 2011

15

Different mechanisms are used by insulin to repress three genes that contain a homologous thymine-rich insulin response element

Satish Patel, Christopher Lipina, Calum Sutherland

Journal:

Year:

2003

Language:

english

File:

PDF, 274 KB

english, 2003

16

Insulin resistance in the brain: An old-age or new-age problem?

Ritchie Williamson, Alison McNeilly, Calum Sutherland

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 405 KB

english, 2012

17

Current Understanding of Intracellular Signalling Pathways || New Connections in the Regulation of PEPCK Gene Expression by Insulin [and Discussion]

Calum Sutherland, Richard M. O'Brien, Daryl K. Granner, J. Saklatvala, P. Cohen and M. F. White

Journal:

Philosophical Transactions Biological Sciences

Year:

1996

Language:

english

File:

PDF, 1.25 MB

english, 1996

18

Novel Procedure To Investigate the Effect of Phosphorylation on Protein Complex Formation in Vitro and in Cells †

Rembutsu, Makoto, Soutar, Marc P. M., Van Aalten, Lidy, Gourlay, Robert, Hastie, C. James, McLauchlan, Hilary, Morrice, Nicholas A., Cole, Adam R., Sutherland, Calum

Journal:

Year:

2008

Language:

english

File:

PDF, 728 KB

english, 2008

19

Zhou et al. reply

Zhou, Kaixin, Bellenguez, Celine, Sutherland, Calum, Hardie, Grahame, Palmer, Colin, Donnelly, Peter, Pearson, Ewan

Journal:

Nature Genetics

Year:

2012

Language:

english

File:

PDF, 162 KB

english, 2012

20

CNP/cGMP signaling regulates axon branching and growth by modulating microtubule polymerization

Xia, Caihong, Nguyen, Minh, Garrison, Amy K., Zhao, Zhen, Wang, Zheng, Sutherland, Calum, Ma, Le

Journal:

Developmental Neurobiology

Year:

2013

Language:

english

File:

PDF, 1.23 MB

english, 2013

21

High fat feeding is associated with stimulation of the hypothalamic-pituitary-adrenal axis and reduced anxiety in the rat

McNeilly, Alison D., Stewart, Caroline A., Sutherland, Calum, Balfour, David J.K.

Journal:

Psychoneuroendocrinology

Year:

2015

Language:

english

File:

PDF, 670 KB

english, 2015

22

GSK-3 Phosphorylation of the Alzheimer Epitope within Collapsin Response Mediator Proteins Regulates Axon Elongation in Primary Neurons

Cole, Adam R., Knebel, Axel, Morrice, Nick A., Robertson, Laura A., Irving, Andrew J., Connolly, Chris N., Sutherland, Calum

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 773 KB

english, 2004

23

AMP-activated Protein Kinase Mediates Phenobarbital Induction of CYP2B Gene Expression in Hepatocytes and a Newly Derived Human Hepatoma Cell Line

Rencurel, Franck, Stenhouse, Alasdair, Hawley, Simon A., Friedberg, Thomas, Hardie, D. Grahame, Sutherland, Calum, Wolf, C. Roland

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 725 KB

english, 2005

24

Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2

Liz, Márcia A, Mar, Fernando M, Santos, Telma E, Pimentel, Helena I, Marques, Ana M, Morgado, Marlene M, Vieira, Sílvia, Sousa, Vera F, Pemble, Hayley, Wittmann, Torsten, Sutherland, Calum, Woodgett,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.67 MB

english, 2014

25

Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling

Eva Kickstein, Sybille Krauss, Paul Thornhill, Désirée Rutschow, Raphael Zeller, John Sharkey, Ritchie Williamson, Melanie Fuchs, Andrea Köhler, Hartmut Glossmann, Rainer Schneider, Calum Sutherland,

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.64 MB

english, 2010

26

Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

Cameron, Amy R., Logie, Lisa, Patel, Kashyap, Bacon, Sandra, Forteath, Calum, Harthill, Jean, Roberts, Adam, Sutherland, Calum, Stewart, Derek, Viollet, Benoit, Sakamoto, Kei, McDougall, Gordon, Foret

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2016

Language:

english

File:

PDF, 860 KB

english, 2016

27

Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis

Grant, Nicola J., Coates, Philip J., Woods, Yvonne L., Bray, Susan E., Morrice, Nicholas A., Hastie, C. James, Lamont, Douglas J., Carey, Francis A., Sutherland, Calum

Journal:

Year:

2015

Language:

english

File:

PDF, 2.95 MB

english, 2015

28

Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure

MORA, Alfonso, LIPINA, Christopher, TRONCHE, François, SUTHERLAND, Calum, ALESSI, Dario R.

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 1.09 MB

english, 2005

29

Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3

Lipina, Christopher, Huang, Xu, Finlay, David, J McManus, Edward, R. Alessi, Dario, Sutherland, Calum

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 468 KB

english, 2005

30

Dissecting Insulin Signaling Pathways: Individualised Therapeutic Targets for Diagnosis and Treatment of Insulin Resistant States

Woods, Yvonne, Petrie, John, Sutherland, Calum

Journal:

Endocrine Metabolic & Immune Disorders - Drug Targets

Year:

2009

Language:

english

File:

PDF, 364 KB

english, 2009

31

A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration

Ruiz-Alcaraz, Antonio J., Liu, Hui-Kang, Cuthbertson, Daniel J., Mcmanus, Edward J., Akhtar, Simeen, Lipina, Christopher, Morris, Andrew D., Petrie, John R., Hundal, Hari S., Sutherland, Calum

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 348 KB

english, 2005

32

Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases

Dayalan Naidu, Sharadha, Sutherland, Calum, Zhang, Ying, Risco, Ana, de la Vega, Laureano, Caunt, Christopher J., Hastie, C. James, Lamont, Douglas J., Torrente, Laura, Chowdhry, Sudhir, Benjamin, Ivo

Journal:

Molecular and Cellular Biology

Year:

2016

Language:

english

File:

PDF, 2.45 MB

english, 2016

33

Tumour necrosis factor α decreases glucose-6-phosphatase gene expression by activation of nuclear factor κB

GREMPLER, Rolf, KIENITZ, Anne, WERNER, Torsten, MEYER, Marion, BARTHEL, Andreas, AILETT, Fabienne, SUTHERLAND, Calum, WALTHER, Reinhard, SCHMOLL, Dieter

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 745 KB

english, 2004

34

Insulin resistance in polycystic ovary syndrome is associated with defective regulation of ERK1/2 by insulin in skeletal muscle in vivo

Rajkhowa, Madhurima, Brett, Sandra, Cuthbertson, Daniel J., Lipina, Christopher, Ruiz-Alcaraz, Antonio J., Thomas, Giles E., Logie, Lisa, Petrie, John R., Sutherland, Calum

Journal:

Biochemical Journal

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

35

Insulin regulation of hepatic insulin-like growth factor-binding protein-1 (IGFBP-1) gene expression and mammalian target of rapamycin (mTOR) signalling is impaired by the presence of hydrogen peroxide

PATEL, Satish, VAN DER KAAY, Jeroen, SUTHERLAND, Calum

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 308 KB

english, 2002

36

Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression

PATEL, Satish, LOCHHEAD, Pamela A., RENA, Graham, SUTHERLAND, Calum

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 301 KB

english, 2001

37

Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression

PATEL, Satish, LOCHHEAD, Pamela A., RENA, Graham, SUTHERLAND, Calum

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 301 KB

english, 2001

38

Dissection of the protein kinase cascades involved in insulin and nerve growth factor action

Cohen, Philip, Campbell, David G., Dent, Paul, Gomez, Nestor, Lavoinne, Alain, Nakielny, Sara, Stokoe, David, Sutherland, Calum, Traverse, Sarah

Journal:

Biochemical Society Transactions

Year:

1992

Language:

english

File:

PDF, 364 KB

english, 1992

39

Models of Dementia: an introductory overview: Table 1

Graham, Lindsay, Sutherland, Calum

Journal:

Biochemical Society Transactions

Year:

2011

Language:

english

File:

PDF, 112 KB

english, 2011

40

Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3

Hayes, John D., Chowdhry, Sudhir, Dinkova-Kostova, Albena T., Sutherland, Calum

Journal:

Biochemical Society Transactions

Year:

2015

Language:

english

File:

PDF, 554 KB

english, 2015

41

Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

Hayes, John D., Ebisine, Kimimuepigha, Sharma, Ritu S., Chowdhry, Sudhir, Dinkova-Kostova, Albena T., Sutherland, Calum

Journal:

Current Opinion in Toxicology

Year:

2016

Language:

english

File:

PDF, 1.89 MB

english, 2016

42

Regulation of Nrf2 by redox and other cellular signalling pathways, and its influence on xenobiotic and lipid metabolism

Hayes, John D., Chowdhry, Sudhir, Sharma, Ritu S., Robertson, Holly, Dinkova-Kostova, Albena T., Dillon, John F., Sutherland, Calum D., Ashford, Michael L.J.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 64 KB

english, 2017

43

A partnership with the proteasome; the destructive nature of GSK3.

Robertson, Holly, Hayes, John D., Sutherland, Calum

Journal:

Biochemical Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.71 MB

english, 2017

44

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3)

Logie, Lisa, Van Aalten, Lidy, Knebel, Axel, Force, Thomas, Hastie, C. James, MacLauchlan, Hilary, Campbell, David G., Gourlay, Robert, Prescott, Alan, Davidson, Jane, Fuller, Will, Sutherland, Calum

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 5.23 MB

english, 2017

45

Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase

Ruiz-Alcaraz, Antonio J., Lipina, Christopher, Petrie, John R., Murphy, Michael J., Morris, Andrew D., Sutherland, Calum, Cuthbertson, Daniel J., Calbet, Jose A. L.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

46

What Are the bona fide GSK3 Substrates?

Sutherland, Calum

Journal:

International Journal of Alzheimer's Disease

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

47

Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice

Muha, Villo, Williamson, Ritchie, Hills, Rachel, McNeilly, Alison D., McWilliams, Thomas G., Alonso, Jana, Schimpl, Marianne, Leney, Aneika C., Heck, Albert J. R., Sutherland, Calum, Read, Kevin D., M

Journal:

Year:

2019

File:

PDF, 1.01 MB

2019

48

Reducing Glut2 throughout the body does not result in cognitive behaviour differences in aged male mice

Morrice, Nicola, van Aalten, Lidy, McNeilly, Alison, McCrimmon, Rory J., Pearson, Ewan R., Langston, Rosamund, Sutherland, Calum

Journal:

BMC Research Notes

Year:

2020

File:

PDF, 903 KB

2020